ITGAE (light chain, Cleaved-Arg177) rabbit pAb
CAT:
855-ES20010-01
Size:
50 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ITGAE (light chain, Cleaved-Arg177) rabbit pAb
- Description: Integrin subunit alpha E (ITGAE) Homo sapiens Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008],
- Synonyms: Integrin alpha-E (HML-1 antigen;Integrin alpha-IEL;Mucosal lymphocyte 1 antigen;CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain]
- Gene ID: 3682
- UniProt: P38570
- Cellular Locus: Membrane; Single-pass type I membrane protein.
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: Synthesized peptide derived from human ITGAE (light chain, Cleaved-Arg177)
- Clonality: Polyclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000;IHC-p 1:50-300
- Molecular Weight: 17 128kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.