Products for Research Use Only
RegisterLogin

[D-Ser14]-Humanin

CAT: 0804-HY-P10611Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P10611Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
[D-Ser14]-Humanin is a bioactive peptide in which the Ser14 residue of Humanin is changed from L-form to D-form. [D-Ser14]-Humanin has potent inhibitory activity against the fibrillation of amyloid-β. Humanin (HY-P1928) inhibits the aging-related death of various cells caused by amyloid fibrils and oxidative stress, and [D-Ser14]-Humanin has better cell protection activity than Humanin (HY-P1928). [D-Ser14]-Humanin can be used in the study of Alzheimer's disease[1].
CAS Number
570382-85-3
UNSPSC
12352209
Target
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-ser14-humanin.html
Smiles
O=C([C@H]1N(CCC1)C([C@H](C)NC([C@@H](N)CCSC)=O)=O)N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CO)C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](C)C(O)=O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C119H204N34O32S2
Molecular Weight
2687.23
References & Citations
[1]Alsanousi, et al. "Solution NMR structure and inhibitory effect against amyloid-β fibrillation of Humanin containing a d-isomerized serine residue." Biochemical and biophysical research communications 477.4 (2016) : 647-653.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P1928-01Humanin
HY-P4567(D-Ser4, D-Trp6) -LHRH
HY-P4563(D-Ser4) -LHRH
HY-P3993(Gly14) -Humanin (human)
HY-P5339Humanin C8A-HN
HY-P4568(D-Ser4, D-Ser (tBu) 6, Azagly10) -LHRH
HY-P3993A-01(Gly14) -Humanin (human) (acetate)
HY-P1851AGA- (C8R) HNG17, humanin derivative
HY-N9914S-01D-Psicose-d
HY-N0379S11-01D-Mannose-d

Alternative Products

CatalogName
TP2803-01[D-Ser14]-Humanin
VAC-00594-01[D-Ser14]-Humanin (HN)
GTR19066642-01[D-Ser14] - Humanin (HN)
GTR18890477[D-Ser14]-Humanin (HN) peptide
abx266893-01[D-Ser14] in (HN) Peptide
hor-042Humanin

Popular Products