(Gly14)-Humanin (human) (acetate)

• UNSPSC Description:

  (Gly14)-Humanin (human) (14-Glycine-Humanin (human)) acetate is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly). (Gly14)-Humanin (human) acetate has anti-apoptotic and neuroprotective functions[1][2].

• Target Antigen:

  Apoptosis

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/gly14-humanin-human-acetate.html

• Purity:

  99.86

• Solubility:

  10 mM in DMSO|H2O : 50 mg/mL (ultrasonic)

• Smiles:

  [MAPRGFSCLLLLTGEIDLPVKRRA (acetate)]

• Molecular Weight:

  2657.21 (free acid)

• References & Citations:

  [1]Ying Xie, et al. Protection effect of [Gly14]-Humanin from apoptosis induced by high glucose in human umbilical vein endothelial cells. Diabetes Res Clin Pract. 2014 Dec;106(3):560-6. |[2]T Wang, et al. [Gly14]-Humanin reduces histopathology and improves functional outcome after traumatic brain injury in mice. Neuroscience. 2013 Feb 12;231:70-81.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported