ATG7-IN-3

ATG7-IN-3

• CAS Number: 2226229-76-9
• UNSPSC Description: ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4[1].
• Target Antigen: Atg7; Atg8/LC3; Autophagy
• Type: Reference compound
• Related Pathways: Autophagy
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atg7-in-3.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CSC1=NN([C@]2([H])O[C@@H]([C@H](C2)O)COS(N)(=O)=O)C3=NC=NC(N)=C31
• Molecular Weight: 376.41
• References & Citations: [1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported