ATG7-IN-3
CAT:
804-HY-146131-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ATG7-IN-3
- CAS Number: 2226229-76-9
- UNSPSC Description: ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4[1].
- Target Antigen: Atg7; Atg8/LC3; Autophagy
- Type: Reference compound
- Related Pathways: Autophagy
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/atg7-in-3.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CSC1=NN([C@]2([H])O[C@@H]([C@H](C2)O)COS(N)(=O)=O)C3=NC=NC(N)=C31
- Molecular Weight: 376.41
- References & Citations: [1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported