ATG7-IN-2

ATG7-IN-2

• CAS Number: 2226227-75-2
• UNSPSC Description: ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].
• Target Antigen: Atg7; Autophagy
• Type: Reference compound
• Related Pathways: Autophagy
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atg7-in-2.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 0.5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O[C@H]1[C@](O[C@@H]([C@H]1O)COS(N)(=O)=O)([H])N2C3=NC=NC(N)=C3C(OC)=N2
• Molecular Weight: 376.35
• References & Citations: [1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported