ATG7-IN-2

• UNSPSC Description:

  ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].

• Target Antigen:

  Atg7; Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/atg7-in-2.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 0.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O[C@H]1[C@](O[C@@H]([C@H]1O)COS(N)(=O)=O)([H])N2C3=NC=NC(N)=C3C(OC)=N2

• Molecular Weight:

  376.35

• References & Citations:

  [1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2226227-75-2