A-1331852
CAT:
804-HY-19741-04
Size:
100 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
A-1331852
- CAS Number: 1430844-80-6
- UNSPSC Description: A-1331852 is an orally available BCL-XL selective inhibitor with a Ki of less than 10 pM.
- Target Antigen: Bcl-2 Family
- Type: Reference compound
- Related Pathways: Apoptosis
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/A-1331852.html
- Purity: 99.93
- Solubility: DMSO : ≥ 50 mg/mL|Ethanol : 4 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)
- Smiles: O=C(C1=NC(N2CC3=C(C=CC=C3C(NC4=NC5=CC=CC=C5S4)=O)CC2)=CC=C1C6=C(C)N(CC7(C8)CC9CC8CC(C9)C7)N=C6)O
- Molecular Weight: 658.81
- References & Citations: [1]Leverson JD, et al. Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy. Sci Transl Med. 2015 Mar 18;7(279):279ra40.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported