Anthopleurin-A

Anthopleurin-A

• UNSPSC Description: Anthopleurin-A is a soidum channel toxin. Anthopleurin-A is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A can be isolated from the sea anemone[1][2].
• Target Antigen: Sodium Channel
• Type: Peptides
• Related Pathways: Membrane Transporter/Ion Channel
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/anthopleurin-a.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H]1NC2=O)C(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC3=CNC=N3)C(NCC(N4[C@@H](CCC4)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@H]2CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(NCC(N8[C@@H](CCC8)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC9=CNC%10=CC=CC=C9%10)C(N[C@@H](CC(C)C)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(N%12[C@@H](CCC%12)C(N[C@@H](CO)C(NCC(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)NC1=O)C(N%13[C@@H](CCC%13)C(N[C@@H](CO)C(NCC(N[C@@H](CC%14=CNC%15=CC=CC=C%14%15)C(N[C@@H](CC%16=CNC=N%16)C(N[C@H]7CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN
• Molecular Weight: 5131.72
• References & Citations: [1]Honma T, Shiomi K. Peptide toxins in sea anemones: structural and functional aspects. Mar Biotechnol (NY). 2006 Jan-Feb;8(1):1-10.|[2]Scriabine A, et al. Cardiotonic effects of anthopleurin-A, a polypeptide from a sea anemone. J Cardiovasc Pharmacol. 1979 Sep-Oct;1(5):571-83.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported