Anthopleurin-A

• Description :

  Anthopleurin-A is a soidum channel toxin. Anthopleurin-A is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A can be isolated from the sea anemone[1][2].

• UNSPSC :

  12352209

• Hazard Statement :

  H301-H311-H330

• Target :

  Sodium Channel

• Type :

  Peptides

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/anthopleurin-a.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H]1NC2=O)C(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC3=CNC=N3)C(NCC(N4[C@@H](CCC4)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@H]2CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(NCC(N8[C@@H](CCC8)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC9=CNC%10=CC=CC=C9%10)C(N[C@@H](CC(C)C)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(N%12[C@@H](CCC%12)C(N[C@@H](CO)C(NCC(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)NC1=O)C(N%13[C@@H](CCC%13)C(N[C@@H](CO)C(NCC(N[C@@H](CC%14=CNC%15=CC=CC=C%14%15)C(N[C@@H](CC%16=CNC=N%16)C(N[C@H]7CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

• Molecular Formula :

  C220H326N64O67S6

• Molecular Weight :

  5131.72

• Precautions :

  P260-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

• References & Citations :

  [1]Honma T, Shiomi K. Peptide toxins in sea anemones: structural and functional aspects. Mar Biotechnol (NY) . 2006 Jan-Feb;8 (1) :1-10.|[2]Scriabine A, et al. Cardiotonic effects of anthopleurin-A, a polypeptide from a sea anemone. J Cardiovasc Pharmacol. 1979 Sep-Oct;1 (5) :571-83.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported