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(S) -SNAP5114

CAT: 0804-HY-103504-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103504-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -SNAP5114 is a selective GABA transport inhibitor, with IC50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively. (S) -SNAP5114 is an anticonvulsant agent[1][2].
CAS Number
157604-55-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-snap5114.html
Purity
98.09
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1CN(CCOC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)CCC1)O
Molecular Formula
C30H35NO6
Molecular Weight
505.60
Precautions
H302, H315, H319, H335
References & Citations
[1]Borden LA, et al. Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site. Receptors Channels. 1994;2 (3) :207-13.|[2]Borden LA, et al. GABA transporter heterogeneity: pharmacology and cellular localization. Neurochem Int. 1996 Oct;29 (4) :335-56.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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