Hexyl gallate

• Description :

  Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR[1]. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM[2].

• Product Name Alternative :

  Hexyl 3,4,5-trihydroxybenzoate

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H317

• Target :

  Bacterial; Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/hexyl-gallate.html

• Concentration :

  10mM

• Purity :

  99.75

• Solubility :

  DMSO : 41.67 mg/mL (ultrasonic)

• Smiles :

  O=C(OCCCCCC)C1=CC(O)=C(O)C(O)=C1

• Molecular Formula :

  C13H18O5

• Molecular Weight :

  254.28

• Precautions :

  H302, H317

• References & Citations :

  [1]Ade Arsianti, et al. Synthesis and in vitro antimalarial activity of alkyl esters of gallate as a growth inhibitor of plasmodium falciparum. Oriental Journal of Chemistry, 34 (2), 655-662.|[2]Kim B, et al. Differential effects of alkyl gallates on quorum sensing in Pseudomonas aeruginosa. Sci Rep. 2019;9 (1) :7741. Published 2019 May 23.|[3]Cavalca LB, et al. Hexyl gallate for the control of citrus canker caused by Xanthomonas citri subsp citri [published online ahead of print, 2020 Aug 6]. Microbiologyopen. 2020; e1104.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Plasmodium

• CAS Number :

  [1087-26-9]