Hexyl gallate

• Description:

  Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR[1]. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM[2].

• Product Name Alternative:

  Hexyl 3,4,5-trihydroxybenzoate

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H317

• Target:

  Bacterial; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/hexyl-gallate.html

• Concentration:

  10mM

• Purity:

  99.75

• Solubility:

  DMSO : 41.67 mg/mL (ultrasonic)

• Smiles:

  O=C (OCCCCCC) C1=CC (O) =C (O) C (O) =C1

• Molecular Formula:

  C13H18O5

• Molecular Weight:

  254.28

• Precautions:

  H302, H317

• References & Citations:

  [1]Ade Arsianti, et al. Synthesis and in vitro antimalarial activity of alkyl esters of gallate as a growth inhibitor of plasmodium falciparum. Oriental Journal of Chemistry, 34 (2), 655-662.|[2]Kim B, et al. Differential effects of alkyl gallates on quorum sensing in Pseudomonas aeruginosa. Sci Rep. 2019;9 (1) :7741. Published 2019 May 23.|[3]Cavalca LB, et al. Hexyl gallate for the control of citrus canker caused by Xanthomonas citri subsp citri [published online ahead of print, 2020 Aug 6]. Microbiologyopen. 2020; e1104.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Plasmodium

• CAS Number:

  1087-26-9