Methyl gallate

• Description:

  Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.

• Product Name Alternative:

  Gallincin; NSC 363001

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Bacterial; HIV; Reactive Oxygen Species (ROS)

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Infection; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/Methyl_gallate.html

• Purity:

  99.98

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(OC)C1=CC(O)=C(O)C(O)=C1

• Molecular Formula:

  C8H8O5

• Molecular Weight:

  184.15

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Kang MS, et al. Inhibitory effect of methyl gallate and gallic acid on oral bacteria. J Microbiol. 2008 Dec;46 (6) :744-50.|[2]Hsieh TJ, et al. Protective effect of methyl gallate from Toona sinensis (Meliaceae) against hydrogen peroxide-induced oxidative stress and DNA damage in MDCK cells. Food Chem Toxicol. 2004 May;42 (5) :843-50.|[3]Lee H, et al. Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. J Immunol. 2010 Dec 1;185 (11) :6698-705.|[4]Wang CR, et al. First report on isolation of methyl gallate with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibitory activities from a mushroom (Pholiota adiposa) . Environ Toxicol Pharmacol. 2014 Mar;37 (2) :626-37.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  HIV-1

• CAS Number:

  99-24-1