β-CGRP, human (TFA)

CAT: 0804-HY-P1548A-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0804-HY-P1548A-01Size:500 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells[1].
Product Name Alternative
Human β-CGRP (TFA) ; CGRP-II (Human) (TFA)
UNSPSC
12352209
Target
CGRP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/_beta_-CGRP,_human_TFA.html
Purity
99.57
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[ACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAF-NH2(Disulfidebridge:Cys2-Cys7)(TFAsalt)]
Molecular Formula
C162H267N51O48S3.xC2HF3O2
Molecular Weight
3793.41 (free base)
References & Citations
[1]McLatchie LM, et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature. 1998 May 28;393 (6683) :333-9.|[2]Russell FA, et al. Calcitonin gene-related peptide: physiology and pathophysiology. Physiol Rev. 2014 Oct;94 (4) :1099-142.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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