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Rat CGRP- (8-37)

CAT: 0804-HY-P0209-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-P0209-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rat CGRP- (8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist.
CAS Number
129121-73-9
UNSPSC
12352209
Target
CGRP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Rat_CGRP-_8-37_.html
Purity
99.57
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
C([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](C(C)C)N)=O)[C@@H](C)O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)C)=O)=O)CC(C)C)=O)CC(C)C)=O)CO)=O)CCCNC(=N)N)=O)CO)=O)=O)=O)C(C)C)=O)[C@H](C)C)=O)CCCCN)=O)CC(O)=O)=O)CC(N)=O)=O)=O)C(C)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)C)=O)CCC(O)=O)=O)CO)=O)=O)[C@@H](C)C)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCC3
Molecular Formula
C138H224N42O41
Molecular Weight
3127.51
References & Citations
[1]Bennett AD, et al. Alleviation of mechanical and thermal allodynia by CGRP (8-37) in a rodent model of chroniccentral pain. Pain. 2000 May;86 (1-2) :163-75.|[2]Yu LC, et al. The calcitonin gene-related peptide antagonist CGRP8-37 increases the latency to withdrawalresponses in rats. Brain Res. 1994 Aug 8;653 (1-2) :223-30.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

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