BITC-SG

BITC-SG

• CAS Number: 62959-30-2
• UNSPSC Description: BITC-SG is the conjugate of phenylisothiocyanate (BITC) and glutathione (GSH). BITC-SG is involved in the irreversible inhibition of GST P1-1[1][2].
• Target Antigen: Glutathione S-transferase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/bitc-sg.html
• Smiles: S=C(NCC1=CC=CC=C1)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O
• Molecular Weight: 456.54
• References & Citations: [1]Meyer DJ, et al., Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates. Biochem J. 1995 Mar 1;306 ( Pt 2)(Pt 2):565-9.|[2]Mathan Kumar S, et al., Regulation of Glutathione in Health and Disease with Special Emphasis on Chronic Alcoholism and Hyperglycaemia Mediated Liver Injury: A Brief Perspective[J]. Springer Science Reviews, 2014, 2: 1-13.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported