BITC-SG

• Description :

  BITC-SG is the conjugate of phenylisothiocyanate (BITC) and glutathione (GSH) . BITC-SG is involved in the irreversible inhibition of GST P1-1[1][2].

• UNSPSC :

  12352005

• Target :

  Glutathione S-transferase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/bitc-sg.html

• Smiles :

  S=C(NCC1=CC=CC=C1)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O

• Molecular Formula :

  C18H24N4O6S2

• Molecular Weight :

  456.54

• References & Citations :

  [1]Meyer DJ, et al., Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates. Biochem J. 1995 Mar 1;306 (Pt 2) (Pt 2) :565-9.|[2]Mathan Kumar S, et al., Regulation of Glutathione in Health and Disease with Special Emphasis on Chronic Alcoholism and Hyperglycaemia Mediated Liver Injury: A Brief Perspective[J]. Springer Science Reviews, 2014, 2: 1-13.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [62959-30-2]