BITC-SG

• UNSPSC Description:

  BITC-SG is the conjugate of phenylisothiocyanate (BITC) and glutathione (GSH). BITC-SG is involved in the irreversible inhibition of GST P1-1[1][2].

• Target Antigen:

  Glutathione S-transferase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bitc-sg.html

• Smiles:

  S=C(NCC1=CC=CC=C1)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O

• Molecular Weight:

  456.54

• References & Citations:

  [1]Meyer DJ, et al., Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates. Biochem J. 1995 Mar 1;306 ( Pt 2)(Pt 2):565-9.|[2]Mathan Kumar S, et al., Regulation of Glutathione in Health and Disease with Special Emphasis on Chronic Alcoholism and Hyperglycaemia Mediated Liver Injury: A Brief Perspective[J]. Springer Science Reviews, 2014, 2: 1-13.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  62959-30-2