CD43 rabbit pAb

CD43 rabbit pAb

• Description: The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011],
• Synonyms: Leukosialin (Galactoglycoprotein;GALGP;Leukocyte sialoglycoprotein;Sialophorin;CD antigen CD43)
• Gene ID: 6693
• UniProt: P16150
• Cellular Locus: Membrane ; Single-pass type I membrane protein. Cell projection, microvillus. Cell projection, uropodium. Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN)..; [CD43 cytoplasmic tail]: Nucleus. Nucleus, PML body. The sumoylated form localizes to the PML body..
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse,
• Immunogen: Synthesized peptide derived from human CD43 AA range: 1-80
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:1000-2000 ELISA 1:5000-20000
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.