EGR-1-IN-2

• UNSPSC Description:

  EGR-1-IN-2 (compound 2) is an EGR-1 inhibitor with anti-inflammatory activity. EGR-1-IN-2 inhibits the formation of EGR-1-DNA complexes induced by TNF-α in HaCaT cells[1].

• Target Antigen:

  TNF Receptor

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/egr-1-in-2.html

• Smiles:

  OC1=CC=C2C=CC=CC2=C1C3=NNC(C3)C4=CC=C(C=C4)OC

• Molecular Weight:

  318.37

• References & Citations:

  [1]Yoon H, et al. Pyrazolines inhibiting the activity of the early growth response-1 DNA-binding domain[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 129952.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  152367-54-9