Methdilazine (hydrochloride)

Methdilazine (hydrochloride)

• CAS Number: 1229-35-2
• UNSPSC Description: Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist). Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases[1][2].
• Target Antigen: Antibiotic; Bacterial; Histamine Receptor
• Type: Reference compound
• Related Pathways: Anti-infection;GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/methdilazine-hydrochloride.html
• Purity: 99.0
• Solubility: DMSO : ≥ 50 mg/mL
• Smiles: CN(CC1)CC1CN2C3=C(C=CC=C3)SC4=C2C=CC=C4.Cl
• Molecular Weight: 332.89
• References & Citations: [1]A N Chakrabarty, et al. Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine. APMIS. 1993 Jun;101(6):449-54. |[2]Noton K Dutta, et al. Activity of the phenothiazine methdilazine alone or in combination with isoniazid or streptomycin against Mycobacterium tuberculosis in mice. J Med Microbiol. 2009 Dec;58(Pt 12):1667-1668.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: Launched