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Methdilazine (hydrochloride)

CAT: 0804-HY-B1690A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1690A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist) . Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases[1][2].
CAS Number
1229-35-2
UNSPSC
12352005
Hazard Statement
H301
Target
Antibiotic; Bacterial; Histamine Receptor
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/methdilazine-hydrochloride.html
Purity
99.90
Solubility
DMSO : ≥ 50 mg/mL
Smiles
CN(CC1)CC1CN2C3=C(C=CC=C3)SC4=C2C=CC=C4.Cl
Molecular Formula
C18H21ClN2S
Molecular Weight
332.89
Precautions
H301
References & Citations
[1]A N Chakrabarty, et al. Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine. APMIS. 1993 Jun;101 (6) :449-54. |[2]Noton K Dutta, et al. Activity of the phenothiazine methdilazine alone or in combination with isoniazid or streptomycin against Mycobacterium tuberculosis in mice. J Med Microbiol. 2009 Dec;58 (Pt 12) :1667-1668.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched