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Methdilazine

CAT: 0804-HY-B1690Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1690Size:1 Each
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Description
Methdilazine is an orally active antibiotic (histamine antagonist) . Methdilazine can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases[1][2].
CAS Number
1982-37-2
UNSPSC
12352005
Target
Antibiotic; Bacterial; Histamine Receptor
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/methdilazine.html
Solubility
10 mM in DMSO
Smiles
CN1CC(CN2C3=C(C=CC=C3)SC4=CC=CC=C24)CC1
Molecular Formula
C18H20N2S
Molecular Weight
296.43
References & Citations
[1]A N Chakrabarty, et al. Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine. APMIS. 1993 Jun;101 (6) :449-54. |[2]Noton K Dutta, et al. Activity of the phenothiazine methdilazine alone or in combination with isoniazid or streptomycin against Mycobacterium tuberculosis in mice. J Med Microbiol. 2009 Dec;58 (Pt 12) :1667-1668.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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