Cathepsin D

• Description:

  Cathepsin D (CTSD) is a lysosomal aspartic protease encoded by the CTSD gene. Cathepsin D regulates lysosomal protease activity. Loss of Cathepsin D leads to lysosomal dysfunction and the accumulation of various cellular proteins associated with neurodegenerative diseases. Cathepsin D is involved in breast cancer metastasis. Cathepsin D can be used in research on diseases such as breast cancer and stroke[1][2].

• Product Name Alternative:

  CTSD

• UNSPSC:

  12352204

• Target:

  Biochemical Assay Reagents

• Type:

  Enzyme

• Related Pathways:

  Others

• Field of Research:

  Cancer; Cardiovascular Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cathepsin-d.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Cathepsin D]

• References & Citations:

  [1]Hossain MI, et al. Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective. Autophagy. 2021 Jun;17 (6) :1330-1348.|[2]Rochefort H, et al. Cathepsin D: a protease involved in breast cancer metastasis. Cancer Metastasis Rev. 1990 Dec;9 (4) :321-31.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20°C for 2 years

• Scientific Category:

  Enzyme

• Clinical Information:

  No Development Reported

• CAS Number:

  9025-26-7