Cathepsin D

• Description :

  Cathepsin D (CTSD) is a lysosomal aspartic protease encoded by the CTSD gene. Cathepsin D regulates lysosomal protease activity. Loss of Cathepsin D leads to lysosomal dysfunction and the accumulation of various cellular proteins associated with neurodegenerative diseases. Cathepsin D is involved in breast cancer metastasis. Cathepsin D can be used in research on diseases such as breast cancer and stroke[1][2].

• Product Name Alternative :

  CTSD

• UNSPSC :

  12352204

• Target :

  Biochemical Assay Reagents

• Type :

  Enzyme

• Related Pathways :

  Others

• Field of Research :

  Cancer; Cardiovascular Disease; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cathepsin-d.html

• Solubility :

  10 mM in DMSO

• Smiles :

  [CathepsinD]

• References & Citations :

  [1]Hossain MI, et al. Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective. Autophagy. 2021 Jun;17 (6) :1330-1348.|[2]Rochefort H, et al. Cathepsin D: a protease involved in breast cancer metastasis. Cancer Metastasis Rev. 1990 Dec;9 (4) :321-31.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20°C for 2 years

• Scientific Category :

  Enzyme

• Clinical Information :

  No Development Reported

• CAS Number :

  [9025-26-7]