Calcium channel-modulator-1

Calcium channel-modulator-1

• CAS Number: 136941-70-3
• UNSPSC Description: Calcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM.
• Target Antigen: Calcium Channel
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/3,5-Pyridinedicarboxylic_acid,_4-_2,3-dichlorophenyl_-1,4-dihydro-2,6-dimethyl-,_methyl_3-_3-oxo-1,2-benzisothiazol-2_3H_-yl_propyl_ester,_S,S-dioxide.html
• Purity: 98.77
• Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC(Cl)=C2Cl)OCCCN(C(C3=C4C=CC=C3)=O)S4(=O)=O
• Molecular Weight: 579.45
• References & Citations: [1]Sunkel CE, et al. Synthesis of 3-[(2,3-dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl)alkyl] 1,4-dihydropyridine-3,5-dicarboxylate derivatives as calcium channel modulators. J Med Chem. 1992 Jun 26;35(13):2407-14.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported