Kiss2 peptide

• UNSPSC Description:

  Kiss2 peptide is a positive regulator of reproduction. Kiss2 peptide binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc)[1].

• Target Antigen:

  Kisspeptin Receptor; PKA; PKC

• Type:

  Peptides

• Related Pathways:

  Epigenetics;GPCR/G Protein;Stem Cell/Wnt;TGF-beta/Smad

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/kiss2-peptide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](N)CC1=CC=CC=C1)N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)CC4=CC=CC=C4)=O)CCC2)=O)CC(N)=O)=O)CC5=CC=CC=C5)=O)CC(N)=O

• Molecular Weight:

  1257.44

• References & Citations:

  [1]Wang B, et al., Inhibitory action of tongue sole LPXRFa, the piscine ortholog of gonadotropin-inhibitory hormone, on the signaling pathway induced by tongue sole kisspeptin in COS-7 cells transfected with their cognate receptors. Peptides. 2017 Sep;95:62-67.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1111070-93-9