Kiss2 peptide

• Description :

  Kiss2 peptide is a positive regulator of reproduction. Kiss2 peptide binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) [1].

• CAS Number :

  [1111070-93-9]

• UNSPSC :

  12352209

• Target :

  Kisspeptin Receptor; PKA; PKC

• Type :

  Peptides

• Related Pathways :

  Epigenetics; GPCR/G Protein; Stem Cell/Wnt; TGF-beta/Smad

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/kiss2-peptide.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](N)CC1=CC=CC=C1)N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)CC4=CC=CC=C4)=O)CCC2)=O)CC(N)=O)=O)CC5=CC=CC=C5)=O)CC(N)=O

• Molecular Formula :

  C63H84N16O12

• Molecular Weight :

  1257.44

• References & Citations :

  [1]Wang B, et al., Inhibitory action of tongue sole LPXRFa, the piscine ortholog of gonadotropin-inhibitory hormone, on the signaling pathway induced by tongue sole kisspeptin in COS-7 cells transfected with their cognate receptors. Peptides. 2017 Sep;95:62-67.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported