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Lipoic acid-d4

CAT: 0804-HY-18733SSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-18733SSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lipoic acid-d4 ((R) - (+) -α-Lipoic acid-d4) is deuterium labeled Lipoic acid. Lipoic acid ((R) - (+) -α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R) - (+) -α-Lipoic acid is more effective than racemic Lipoic acid[1].
CAS Number
1448263-85-1
Product Name Alternative
(R) - (+) -α-Lipoic acid-d4; R- (+) -Thioctic acid-d4
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Smiles
O=C(CC([2H])(C([2H])(C[C@H]1SSCC1)[2H])[2H])O
Molecular Formula
C8H10D4O2S2
Molecular Weight
210.35
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Nasole E, et al. Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-α and EGF production in chronic leg wound healing. J Enzyme Inhib Med Chem. 2014 Apr;29 (2) :297-302.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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