Caloxin 2A1 (TFA)

Caloxin 2A1 (TFA)

• UNSPSC Description: Caloxin 2A1 TFA is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 TFA does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].
• Target Antigen: Proton Pump
• Type: Peptides
• Related Pathways: Membrane Transporter/Ion Channel
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/caloxin-2a1-tfa.html
• Purity: 99.96
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
• Smiles: O=C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(N[C@@H](CO)C(N[C@@H](CO)C(NCC(NCC(NCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@@H](N)C(C)C)=O)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45.OC(C(F)(F)F)=O
• Molecular Weight: 1592.54
• References & Citations: [1]J Chaudhary, et al. Caloxin: a novel plasma membrane Ca2+ pump inhibitor. Am J Physiol Cell Physiol. 2001 Apr;280(4):C1027-30.|[2]Yi-fei Chen, et al. Plasma membrane Ca2+-ATPase regulates Ca2+ signaling and the proliferation of airway smooth muscle cells. Eur J Pharmacol. 2014 Oct 5;740:733-41.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported