Procyanidin B2

Procyanidin B2

• CAS Number: 29106-49-8
• UNSPSC Description: Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.
• Target Antigen: Reactive Oxygen Species
• Type: Natural Products
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/Procyanidin-B2.html
• Purity: 99.89
• Solubility: DMSO : ≥ 50 mg/mL|H2O : 66.67 mg/mL (ultrasonic)
• Smiles: O[C@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3[C@@H]1C4=C5C(C[C@@H](O)[C@@H](C6=CC=C(O)C(O)=C6)O5)=C(O)C=C4O
• Molecular Weight: 578.52
• References & Citations: [1]Avelar MM, et al. Procyanidin b2 cytotoxicity to mcf-7 human breast adenocarcinoma cells. Indian J Pharm Sci. 2012 Jul;74(4):351-5.|[2]Yang H, et al. Procyanidin B2 inhibits NLRP3 inflammasome activation in human vascular endothelial cells. Biochem Pharmacol. 2014 Dec 15;92(4):599-606.|[3]Wu S, et al. Procyanidin B2 attenuates neurological deficits and blood-brain barrier disruption in a rat model of cerebral ischemia. Mol Nutr Food Res. 2015 Oct;59(10):1930-41.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported