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Peanut procyanidin A

CAT: 0804-HY-N13174Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N13174Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Peanut procyanidin A is a type of A-type procyanidin that can be extracted from peanut skins. Peanut procyanidin A can protect prostate DU145 cells from H2O2-induced oxidative stress damage through the MAPKs signaling pathway, alleviate cell cycle arrest, and reduce cell apoptosis. Peanut procyanidin A can also regulate gut microbiota and metabolism in mice with DSS -induced ulcerative colitis[1][2].
CAS Number
1802175-67-2
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/peanut-procyanidin-a.html
Smiles
O[C@H]([C@H](C(C=C1)=CC(O)=C1O)O2)[C@H](C(C2=CC(O)=C3)=C3O)C4=C(O)C(O)=CC5=C4O[C@@](C6=CC=C(O)C(O)=C6)(O7)[C@H](O)[C@H]5C(C(O[C@@H]8C(C=C9)=CC(O)=C9O)=C%10C[C@@H]8O)=C7C=C%10O
Molecular Formula
C45H36O18
Molecular Weight
864.76
References & Citations
[1]Yan F, et al. Protective effect of procyanidin A-type dimers against H2O2-induced oxidative stress in prostate DU145 cells through the MAPKs signaling pathway. Life Sci. 2021 Feb 1;266:118908. |[2]Huang B, et al. The underlying mechanism of A-type procyanidins from peanut skin on DSS-induced ulcerative colitis mice by regulating gut microbiota and metabolism. J Food Biochem. 2022 Jul;46 (7) :e14103.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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