Peanut procyanidin A

Peanut procyanidin A

• CAS Number: 1802175-67-2
• UNSPSC Description: Peanut procyanidin A is a type of A-type procyanidin that can be extracted from peanut skins. Peanut procyanidin A can protect prostate DU145 cells from H2O2-induced oxidative stress damage through the MAPKs signaling pathway, alleviate cell cycle arrest, and reduce cell apoptosis. Peanut procyanidin A can also regulate gut microbiota and metabolism in mice with DSS (HY-116282)-induced ulcerative colitis[1][2].
• Target Antigen: Apoptosis; Reactive Oxygen Species
• Type: Natural Products
• Related Pathways: Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/peanut-procyanidin-a.html
• Smiles: O[C@H]([C@H](C(C=C1)=CC(O)=C1O)O2)[C@H](C(C2=CC(O)=C3)=C3O)C4=C(O)C(O)=CC5=C4O[C@@](C6=CC=C(O)C(O)=C6)(O7)[C@H](O)[C@H]5C(C(O[C@@H]8C(C=C9)=CC(O)=C9O)=C%10C[C@@H]8O)=C7C=C%10O
• Molecular Weight: 864.76
• References & Citations: [1]Yan F, et al. Protective effect of procyanidin A-type dimers against H2O2-induced oxidative stress in prostate DU145 cells through the MAPKs signaling pathway. Life Sci. 2021 Feb 1;266:118908. |[2]Huang B, et al. The underlying mechanism of A-type procyanidins from peanut skin on DSS-induced ulcerative colitis mice by regulating gut microbiota and metabolism. J Food Biochem. 2022 Jul;46(7):e14103.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported