FLT3-IN-4

FLT3-IN-4

• CAS Number: 2304799-09-3
• UNSPSC Description: FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia[1].
• Target Antigen: FLT3
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/flt3-in-4.html
• Purity: 99.73
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: C=CCN1C2=NC=NC(N)=C2C(C3=CC=C(NC(NC4=NOC(C(C)(C)C)=C4)=O)C=C3)=C1
• Molecular Weight: 431.49
• References & Citations: [1]Yuan X, et al. Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia. J Med Chem. 2019 Apr 25;62(8):4158-4173.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported