NSE Antibody / Neuron Specific Enolase

• Description:

  This monoclonal antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found predominantly in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas.It it be usually employed in combination with other markers such as Synaptophysin, ?Chromogranin A, and Neurofilament.

• UniProt:

  P09104

• Host:

  Mouse

• Immunogen:

  A recombinant fragment of human NSE gamma (within amino acids 150-300) was used as the immunogen for the NSE gamma antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Applications:

  IHC-P, WB

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the NSE gamma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This NSE gamma antibody is available for research use only.

• CAS Number:

  9007-83-4