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Myocyte enhancer factor 2A Antibody / MEF2A

CAT: 0800-RQ8377Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ8377Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
Q02078
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide derived from human Myocyte enhancer factor 2A protein was used as the immunogen for the Myocyte enhancer factor 2A antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28M44
Type
Recombinant
Applications
WB
Purity
Affinity chromatography
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Myocyte enhancer factor 2A antibody at -20oC.
Limitations
This Myocyte enhancer factor 2A antibody is available for research use only.
Storage Conditions
Store the Myocyte enhancer factor 2A antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Myocyte enhancer factor 2A antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with Myocyte enhancer factor 2A antibody. Predicted molecular weight: 46-55 kDa (multiple isoforms) .

UniProtKB · Q02078

Myocyte-specific enhancer factor 2A

MEF2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02078
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MEF2A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DFQ7, F6XG23, O43814, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDevelopmental proteinDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDifferentiationNeurogenesisTranscriptionTranscription regulation

Disease

Disease variant

Cellular component

Nucleus

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