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POLR1C Antibody

CAT: 0800-RQ8085Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8085Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNA-directed RNA polymerases I and III subunit RPAC1 is a protein that in humans is encoded by the POLR1C gene. The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
O15160
Host
Rabbit
Reactivity
Human
Immunogen
E. coli-derived recombinant human protein (amino acids K47-D346) was used as the immunogen for the POLR1C antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the POLR1C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This POLR1C antibody is available for research use only.
Storage Conditions
After reconstitution, the POLR1C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the POLR1C antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of fixed and permeabilized human RT4 cells with POLR1C antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= POLR1C antibody.

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