Rage Antibody / Ager

CAT: 0800-RQ8039Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ8039Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enables S100 protein binding activity; advanced glycation end-product binding activity; and heparin binding activity. Involved in several processes, including cellular response to amyloid-beta; negative regulation of long-term synaptic potentiation; and positive regulation of cytokine production. Acts upstream of or within several processes, including induction of positive chemotaxis; negative regulation of advanced glycation end-product receptor activity; and positive regulation of macromolecule metabolic process. Located in extracellular space and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and lung. Human ortholog (s) of this gene implicated in several diseases, including autoimmune disease (multiple) ; cardiovascular system disease (multiple) ; cystic fibrosis; kidney failure (multiple) ; and lupus nephritis. Orthologous to human AGER (advanced glycosylation end-product specific receptor) .
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q62151
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
E. coli-derived recombinant mouse protein (amino acids Q24-E320) was used as the immunogen for the Rage antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Rage antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Rage antibody is available for research use only.
Storage Conditions
After reconstitution, the Rage antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Rage antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat lung and 2) mouse lung tissue lysate with Rage antibody. Expected molecular weight: 45-55 kDa depending on glycosylation level.

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