Rage Antibody

• Description:

  RAGE, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family. The interaction between RAGE and its ligands, AGE and HMGB1, is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. [Wiki]

• Specifications:

  Western blot: 1:1000

• UniProt:

  Q9WVS4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A portion of amino acids 76-104 from the mouse protein was used as the immunogen for this Rage antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the Rage antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Rage antibody is available for research use only.

• Storage Conditions:

  Aliquot the Rage antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the Rage antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Rage antibody western blot analysis in NCI-H292 lysate. Predicted molecular weight: 45-55kDa depending on glycosylation level.