Products for Research Use Only
RegisterLogin

Physcion-d3

CAT: 0804-HY-N0108S-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0108S-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Physcion-d3 (Parietin-d3) is the deuterium labeled Physcion. Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects[1][2][3].
CAS Number
1215751-27-1
Product Name Alternative
Parietin-d3; Rheochrysidin-d3
UNSPSC
12352005
Target
Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Purity
99.82
Solubility
DMF : 1mg/mL (ultrasonic) |DMSO : 3.33mg/mL (ultrasonic; warming; adjust pH to 9 with NaOH; heat to 60°C) |THF : 2.5mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=CC(OC([2H])([2H])[2H])=CC(O)=C2C(C3=C(O)C=C(C)C=C31)=O
Molecular Formula
C16H9D3O5
Molecular Weight
287.28
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Lin R, et al. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17 (11) :1484-96.|[3]Pang MJ, et al. Physcion, a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinoma. Acta Pharmacol Sin. 2016 Dec;37 (12) :1623-1640.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N0108-01Physcion
HY-N0108R-01Physcion (Standard)
HY-N16588Cis-Emodin-physcion bianthrone
HY-N10371-01Physcion-8-O-β-gentiobioside
HY-N8962Physcion 8-O-rutinoside
HY-N5091Physcion 8-O-β-D-glucopyranoside
HY-N12575Physcion-8-O- (6'-O-malonyl) -glucoside
HY-15398S3-01Vitamin D3-d3
HY-132348S1Granisetron-d3 (1-methyl-d3)
HY-150954SL-Methionine-d3 (S-methyl-d3) Methyl-d3-sulfonium Chloride

Alternative Products

CatalogName
TRC-P398002-1MGPhyscion-d3
TB0045Physcion

Popular Products