Complement factor I

• Description:

  Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) [1].

• UNSPSC:

  12352204

• Target:

  Endogenous Metabolite

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/complement-factor-i.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [ComplementfactorI]

• References & Citations:

  [1]Zhang Y, et al. Complement Factor I Variants in Complement-Mediated Renal Diseases. Front Immunol. 2022 May 10;13:866330.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Enzyme

• Clinical Information:

  No Development Reported

• CAS Number:

  [80295-66-5]