Complement factor D

• Description :

  Complement factor D is a serine protease. Complement factor D activates C3 convertase by specifically cleaving complement Factor B. Complement factor D is promising for research of autoimmune diseases (e.g., paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy), age-related macular degeneration, and thrombotic microangiopathies[1].

• UNSPSC :

  12352204

• Target :

  Ser/Thr Protease

• Type :

  Enzyme

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/complement-factor-d.html

• Solubility :

  10 mM in DMSO

• Smiles :

  [ComplementfactorD]

• References & Citations :

  [1]Barratt J, et al. Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway. Front Immunol. 2021 Sep 9;12:712572.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Enzyme

• Clinical Information :

  No Development Reported

• CAS Number :

  [37213-56-2]