Complement factor D

• Description:

  Complement factor D is a serine protease. Complement factor D activates C3 convertase by specifically cleaving complement Factor B. Complement factor D is promising for research of autoimmune diseases (e.g., paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy), age-related macular degeneration, and thrombotic microangiopathies[1].

• UNSPSC:

  12352204

• Target:

  Ser/Thr Protease

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/complement-factor-d.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Complement factor D]

• References & Citations:

  [1]Barratt J, et al. Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway. Front Immunol. 2021 Sep 9;12:712572.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Enzyme

• Clinical Information:

  No Development Reported

• CAS Number:

  37213-56-2