Complement factor D-IN-2

• Description:

  Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases[1].

• UNSPSC:

  12352005

• Target:

  Complement System

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/complement-factor-d-in-2.html

• Purity:

  99.33

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C ([C@H]1N (C (CN2N=C (C (C) =O) C3=C2C=CC (C4=CN=C (C) N=C4) =C3) =O) [C@]5 ([H]) C[C@]5 ([H]) C1) NC6=NC (Br) =CC=C6

• Molecular Formula:

  C27H24BrN7O3

• Molecular Weight:

  574.43

• References & Citations:

  [1]GADHACHANDA VR, et, al. Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders. WO2015130838A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1903742-34-6