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AMPK beta 2 Polyclonal Antibody

CAT: 0965-JOT-AP14212-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14212-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
CAS Number
9007-83-4
Synonyms
5'-AMP-activated protein kinase subunit beta-2; PRKAB2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein of AMPKβ2
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Antibody Type
Primary antibody
Isotype
IgG