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AMPK alpha2 Polyclonal Antibody

CAT: 0965-JOT-AP14210-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14210-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
CAS Number
9007-83-4
Synonyms
5'-AMP-activated protein kinase catalytic subunit alpha-2; PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein of AMPKα2
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Antibody Type
Primary antibody
Isotype
IgG

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