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NHRF1 Polyclonal Antibody

CAT: 0965-JOT-AP13945-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP13945-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2| and loss of heterozygosity of this gene is implicated in breast cancer.
CAS Number
9007-83-4
Synonyms
Na;+/H;+ exchange regulatory cofactor NHE-RF1 ;NHERF-1;Ezrin-radixin-moesin-binding phosphoprotein 50;EBP50;Regulatory cofactor of Na;+/H;+ exchanger;Sodium-hydrogen exchanger regulatory f
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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