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CRSP34 Polyclonal Antibody

CAT: 0965-JOT-AP02251-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02251-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED27 (mediator complex subunit 27) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for MED27, and a pseudogene of MED27 is located on the long arm of chromosome 5.
CAS Number
9007-83-4
Synonyms
MED27; CRSP34; CRSP8; Mediator of RNA polymerase II transcription subunit 27; Cofactor required for Sp1 transcriptional activation subunit 8; CRSP complex subunit 8; Mediator complex subunit 27; P37 T
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
Synthesized peptide derived from CRSP34 . at AA range: 90-170
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
35432
Antibody Type
Primary antibody
Isotype
IgG

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