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8ODP Polyclonal Antibody

CAT: 0965-JOT-AP08520-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08520-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates| such as 8-oxo-dGTP| 8-oxo-dATP| 2-hydroxy-dATP| and 2-hydroxy rATP| to monophosphates| thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm| with some in the mitochondria| suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants| some of which encode distinct isoforms| have been identified. Additional variants have been observed| but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional| longer is
CAS Number
9007-83-4
Synonyms
7; 8-dihydro-8-oxoguanine triphosphatase ;EC 3.6.1.55;2-hydroxy-dATP diphosphatase;EC 3.6.1.56;8-oxo-dGTPase;Nucleoside diphosphate-linked moiety X motif 1;Nudix motif 1
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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