TIF1 Alpha Polyclonal Antibody

CAT: 0965-JOT-AP09021-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0965-JOT-AP09021-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Transcription intermediary factor 1-alpha encoded by TRIM24 mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

CAS Number

9007-83-4

Synonyms

TRIM24; RNF82; TIF1; TIF1A; Transcription intermediary factor 1-alpha; TIF1-alpha; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; Tripartite motif-containing protein 24

Host

Rabbit

Reactivity

Human;Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TRIM24. AA range:1001-1050

Clonality

Polyclonal

Applications

WB, IHC-p, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

116831

Antibody Type

Primary antibody

Isotype

IgG

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