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Sin3B Polyclonal Antibody

CAT: 0965-JOT-AP08319-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08319-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SIN3B (SIN3 Transcription Regulator Family Member B) is a Protein Coding gene. Paired amphipathic helix protein Sin3b acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. Among its related pathways are Gene Expression and Metabolism. Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase II transcription corepressor activity. An important paralog of this gene is SIN3A.
CAS Number
9007-83-4
Synonyms
SIN3B; KIAA0700; Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human SIN3B. AA range:221-270
Clonality
Polyclonal
Applications
WB, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
133066
Antibody Type
Primary antibody
Isotype
IgG

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