SIN3B Polyclonal Antibody

• Background:

  Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

• Description:

  This is a SIN3B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SIN3B

• Gene ID:

  23309

• Swiss Prot:

  O75182

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human SIN3B

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:1000-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  36kDa

• Observed Molecular Weight:

  36kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG