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PTP22 Polyclonal Antibody

CAT: 0965-JOT-AP07492-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07492-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PTPN22 encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The protein tyrosine phosphatase, non-receptor type 22 is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
CAS Number
9007-83-4
Synonyms
PTPN22; PTPN8; Tyrosine-protein phosphatase non-receptor type 22; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; LyP; PEST-domain phosphatase; PEP
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human PTP22.
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
91705
Antibody Type
Primary antibody
Isotype
IgG

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