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PCB Polyclonal Antibody

CAT: 0965-JOT-AP06969-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06969-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PC encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
CAS Number
9007-83-4
Synonyms
PC; Pyruvate carboxylase; mitochondrial; Pyruvic carboxylase; PCB
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PC. AA range:357-406
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
129634
Antibody Type
Primary antibody
Isotype
IgG

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