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Patched Polyclonal Antibody

CAT: 0965-JOT-AP06944-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06944-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PTCH1 (patched 1) encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of PTCH1 have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
CAS Number
9007-83-4
Synonyms
PTCH1; PTCH; Protein patched homolog 1; PTC; PTC1
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
160561
Antibody Type
Primary antibody
Isotype
IgG

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