Products for Research Use Only
RegisterLogin

PAF-R Polyclonal Antibody

CAT: 0965-JOT-AP06881-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP06881-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
PTAFR (platelet activating factor receptor) encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
PTAFR; PAFR; Platelet-activating factor receptor; PAF-R; PAFr
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PTAFR. AA range:194-243
Clonality
Polyclonal
Applications
IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
39203
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP06325-01Ob-R Polyclonal Antibody
JOT-AP06150-01NPY5-R Polyclonal Antibody
JOT-AP06147-01NPY1-R Polyclonal Antibody
JOT-AP05261-01MC1-R Polyclonal Antibody
JOT-AP04948-01Laminin-R Polyclonal Antibody
JOT-AP03563-01GHRH-R Polyclonal Antibody
JOT-AP03635-01GnRH-R Polyclonal Antibody
JOT-AP14855-01Tenascin-R Polyclonal Antibody
JOT-AP06148-01NPY2-R Polyclonal Antibody
JOT-AP06324-01Ob-R Polyclonal Antibody

Alternative Products

CatalogName
MBS8524547-01PAF-R Polyclonal Antibody
APRab15693-01PAF-R Rabbit Polyclonal Antibody
WP13851-01U-Blot® PAF-R Polyclonal Antibody
PA90205HU-01Rabbit Anti-Human PAF-R Polyclonal Antibody
bs-1119RPAF Polyclonal Antibody
TMAB-01325-01Anti-PAF Polyclonal Antibody
GTR18093690PAF Rabbit Polyclonal Antibody
GTR17750798PAF Rabbit Polyclonal Antibody (PE)
BS65779-01PAFR/PAF Receptor Polyclonal Antibody
bs-1119R-PEPAF Polyclonal Antibody, PE Conjugated

Popular Products