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GnRH-R Polyclonal Antibody

CAT: 0965-JOT-AP03635-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03635-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GNRHR encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.
CAS Number
9007-83-4
Synonyms
GNRHR; GRHR; Gonadotropin-releasing hormone receptor; GnRH receptor; GnRH-R
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human GNRHR. AA range:41-90
Clonality
Polyclonal
Applications
WB, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
37731
Antibody Type
Primary antibody
Isotype
IgG

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