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Ob-R Polyclonal Antibody

CAT: 0965-JOT-AP06325-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06325-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID: 54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID: 9207021).
CAS Number
9007-83-4
Synonyms
LEPR; DB; OBR; Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD antigen CD295
Host
Rabbit
Reactivity
Human;Mouse;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human Leptin Receptor. AA range:1107-1156
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
132494
Antibody Type
Primary antibody
Isotype
IgG

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